DINASE 30-30 Dry®
On a free flowing Silicon Dioxide Carrier

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All you want to know about DINASE 30-30 ® as a Urease Inhibitor
What is DINASE 30-30 Dry® ?

DINASE 30-30 Dry® is a new high technology feed additive that inhibits urease activity and therefore reduces ammonia gas levels and other odors in the organic waste of the animal, and the environment.

How does the enzyme urease produce ammonia?
Urease enzyme converts urea and other nitrogenous compounds to ammonia and carbon dioxide. Increase dietary protein will also increase ammonia excretion.

What is the active ingredient of DINASE 30-30 Dry® ?
DINASE 30-30 Dry® is a naturally concentrated extract of the Yucca Schidigera plant obtained through a low temperature pressing process, thereby assuring retention of natural ingredients and efficacy. The extracts are then absorbed by a high tech mineral carrier. Other brands may be heat extracted which destroys the active ingredient.

How does DINASE 30-30 Dry® work?
DINASE 30-30 Dry- inhibits urease activity in the intestines.
DINASE 30-30 DryDry reduces ammonia concentration in intestines.
DINASE 30-30 Dry decreases PVDO (Portal Vein Drained Organs) mucosal tissue turn-over rate.
DINASE 30-30 Dry reduces oxygen and nutrient demand of PVDO (Portal Vein Drained Organs) therefore making these available for improved growth and feed conversion. Example of improved performance.

Why is ammonia gas dangerous to animal health?
Ammonia is an irritating and toxic gas that is excreted in the feces and urine of animals. This gas must therefore be detoxified in the liver which uses energy which is suppose to be conserved by the animal for muscle building and other productive purposes.
As a result of continued exposure to ammonia, feed intake, sexual maturity and rate of lay will be affected negatively. Aerial ammonia likewise, increase the incidence of respiratory infections due to irritation in the respiratory tract.
Feed conversion efficiency is also affected which is very uneconomical for the raiser. It is therefore important for the raiser to have an awareness for the potential loss in the performance of animals exposed to prolonged high levels of ammonia.

In Pigs 4.5%, better feed efficacy and 4.9% better growth.
In Layers 4-6, more eggs.
In Dairy Cattle, 3.5 lbs more milk/cow/day.
In Broilers, 40% reduction in ascites mortality

How are we going to detect ammonia in the animal house?
A rule of thumb is that if there is a burning sensation to the human eye, then the atmospheric ammonia is 50 ppm or above. There are other objective methods of measurement . Please call our office for more information.

What is the advantage of DINASE 30-30 Dry® as a urease inhibitor against an ammonia binding product?
Based on tests conducted, DINASE 30-30 Dry® not only diminishes ammonia emanations but urease activity as well, so that the effect is not that of ammonia binding but inhibition of the urease enzyme. This is the technological advantage of a UREASE INHIBITOR like DINASE 30-30 Dry® over AMMONIA BINDING products.

To better explain, one enzyme can continue to break down urea to carbon dioxide and ammonia almost indefinitely unless somehow damaged. This would mean that, for example, with a life rotation of 1,000 to 1 urease enzyme, the amount of ammonia that we have to bind would be 1,000 fold compared to the amount of the enzymes that would have to be inhibited to produce similar results.

For this reason DINASE 30-30 Dry® as a urease inhibitor has a much more effective technology than binding ammonia. Our investigation shows that there is a direct inhibitory effect over the urease enzyme which diminishes ammonia and carbon dioxide emanations.

DINASE 30-30 Dry-15 Dry-15 Dry® can inhibit urease enzyme approximately 50 % which is the most effective treatment range. This results in 50 % reduction in ammonia levels in the intestine and in the environment.

Aside from ammonia, can DINASE 30-30 Dry-15 Dry-15 Dry® also inhibit other gases or odor ?
Yes. Studies in dogs showed a 50 % reduction of skatole and indole in dog’s feces fed with DINASE 30-30 Dry-15 Dry-15 Dry®. (Skatole and indole are the by-products of bacterial degradation of amino acids. These are also the compounds that are responsible for the boar odor in swine.) It was concluded that the reduction was due to the alteration of bacterial population in the intestine of the animals.

What are the economic advantages that we can get from using DINASE 30-30 Dry®?

Results from swine and poultry experiments abroad revealed the following:
In swine, DINASE 30-30 Dry ® : Reduces environmental ammonia by 50%
Reduces intestinal ammonia by 50 – 60 %
Improves Feed Conversion Ratio (FCR) by 4%
Improves weight gain by 4%
Increases weaned pigs/sow/year by 1.3

In broilers, DINASE 30-30 Dry® : Weight gain increases by 2%
Improves Feed Conversion Ratio (FCR) by 2%
Reduces ascites mortality by 40%

How much DINASE 30-30 Dry® will I put in feeds or in water ?

DINASE 30-30 Dry® is prepared in two basic forms:

Product Specifications

Color Medium to light tan powder.
Guaranteed Analysis Storage 30 % Natural Yucca Schidigera
extract supplement.Dry and cool environment. Keepcontainer closed.
Saponin con-
tent (%), (ppm) 
~14-16 %, with 10% variability.
Saponin content140-160,000 ppm.
For Use in Poultry, pigs, dairy cattle, aquatic,
equines and pet feeds.
Directions Use as recommended up to 160
grams per metric ton.
Bulk density 22 lbs. per cubic ft.
Particle size 60 mesh
Listed as

GRAS (Generally Recognized As Safe).

Recommended Dosage

Broilers Grams / M.T.
Broilers 160
Layers 53
Turkeys 160
Cattle (meat and dairy) 0.88 mg/kg of weight to maximum 340 mg/head/day.
Horses 0.88 mg/kg of weight to maximum 300mg/head/day.
Starter 125
Lactating Sows 90
Grower 45
Finisher 62.5
Gestating sows 62.5
Rabbits 48
Cats 48
Dogs 92
Aquatic Species 48